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RPS6KA5 (Ab-376) Polyclonal Antibody
MSK1; RLPK; MSPK1
货号:YBAP12266
价格: 980/1280/1890
Immunogen: Synthetic peptide of human RPS6KA5 (Ab-376)
Synonym:
MSK1; RLPK; MSPK1
Calculated MW: 90kDa
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M,R;

Clonality: Polyclonal


Application:
WB
Purify:
Affinity purification
Concentration:
1mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
RPS6KA5 (Ab-376) Polyclonal Antibody


Western blot analysis of HUVEC cells , using RPS6KA5 (Ab-376) Polyclonal Antibody at dilution of 1:500

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).

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