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SFRP1 Polyclonal Antibody
FRP, FRP1, FrzA, FRP-1, SARP2
货号:YBAP12573 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Synthetic peptide of human SFRP1 | ||
Synonym: |
FRP, FRP1, FrzA, FRP-1, SARP2 | ||
Calculated MW: | |||
Observed MW: | |||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
0.6mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Immunohistochemistry of Human esophagus cancer using SFRP1 Polyclonal Antibody at dilution of 1:15 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. Interacts with WNT1, WNT2 and FRZD6. Interacts with WNT4 and WNT8.
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