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HSD17B1 Polyclonal Antibody
HSD17; EDHB17; EDH17B2; SDR28C1
货号:YBAP13561
价格: 980/1280/1890
Immunogen: Synthetic peptide of human HSD17B1
Synonym:
HSD17; EDHB17; EDH17B2; SDR28C1
Calculated MW: 35kDa
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H;

Clonality: Polyclonal


Application:
ELISA WB IHC
Purify:
Affinity purification
Concentration:
2.8mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
HSD17B1 Polyclonal Antibody


Western blot analysis of Human placenta tissue , using HSD17B1 Polyclonal Antibody at dilution of 1:700

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
Hydroxysteroid (17-beta) dehydrogenase 1 catalyzes the final step in the formation of estradiol and testosterone from estrone and androstenedione, respectively. Ovarian granulosa cells and breast tissue both express HSD17B1. Other tissues that express HSD17B1 include testis, placenta, uterus, prostate and adipose tissue. HSD17B1 functions as a homodimer and prefers NADP(H) over NAD(H) for oxidation and reduction. The gene encoding human HSD17B1 maps to chromosome 17q12-q21. The importance of HSD17B1 to estradiol production suggests the specific inhibition of HSD17B1 may aid in breast cancer therapy.

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