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SIGLEC8 Polyclonal Antibody
SAF2; SIGLEC-8; SIGLEC8L
货号:YBAP13875 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Synthetic peptide of human SIGLEC8 | ||
Synonym: |
SAF2; SIGLEC-8; SIGLEC8L | ||
Calculated MW: | |||
Observed MW: | |||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
2.4mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Immunohistochemistry of Human brain using SIGLEC8 Polyclonal Antibody at dilution of 1:40 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein.
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