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APIP Polyclonal Antibody
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2
货号：YBAP14110 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human APIP | ||
Synonym: |
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2 | ||
| Calculated MW: | 27kDa | ||
| Observed MW: | Refer to figures | ||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H,M; Clonality: Polyclonal  |
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Application: |
ELISA WB IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
0.6mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Western blot analysis of Mouse heart tissue, using APIP Polyclonal Antibody at dilution of 1:300 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.
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