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CDK4 Polyclonal Antibody
CMM3, PSK-J3
货号:YBAP14248
价格: 980/1280/1890
Immunogen: Recombinant protein of human CDK4
Synonym:
CMM3, PSK-J3
Calculated MW: 34kDa
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M,R;

Clonality: Polyclonal


Application:
ELISA WB IHC
Purify:
Affinity purification
Concentration:
0.9mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
CDK4 Polyclonal Antibody


Western blot analysis of Hela and 293T cell, using CDK4 Polyclonal Antibody at dilution of 1:450

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.

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