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RB1 Polyclonal Antibody
RB; pRb; OSRC; pp110; p105-Rb
货号:YBAP14534 |
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规格: 50ul/100ul/200ul |
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价格: 980/1280/1890 |
Immunogen: | Recombinant protein of human RB1 | ||
Synonym: |
RB; pRb; OSRC; pp110; p105-Rb | ||
Calculated MW: | 106kDa | ||
Observed MW: | Refer to figures | ||
Source: |
Rabbit |
Isotype: |
IgG | ||
Application: |
ELISA WB | ||
Purify: |
Affinity purification | ||
Concentration: |
2.1mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
Western blot analysis of A431 cell, using RB1 Polyclonal Antibody at dilution of 1:500 |
Protocols: |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma
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