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CDKN2AIP Polyclonal Antibody
CARF
货号：YBAP14542 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human CDKN2AIP | ||
Synonym: |
CARF | ||
| Calculated MW: | |||
| Observed MW: | |||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H; Clonality: Polyclonal  |
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Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
0.9mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Immunohistochemistry of Human brain using CDKN2AIP Polyclonal Antibody at dilution of 1:20 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
CDKN2AIP (CDKN2A-interacting protein), also known as CARF, is a 580 amino acid protein that activates p53 via p14 ARF (alternate reading frame)-dependent and independent pathways. CDKN2AIP-dependent activation of p53, a protein that up-regulates growth arrest and apoptosis-related genes in response to stress signals, leads to an enhancement of p53 function. Expression levels of CDKN2AIP and p53 show an inverse relationship that is caused by a negative-feedback control via a proteasome-mediated degradation pathway. CDKN2AIP is expressed ubiquitously across tissue samples and, along with p14 ARF, is localized to the perinucleolar region within the nucleus.
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