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GPM6A Polyclonal Antibody
M6A; GPM6
货号：YBAP15017 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human GPM6A | ||
Synonym: |
M6A; GPM6 | ||
| Calculated MW: | 31kDa | ||
| Observed MW: | Refer to figures | ||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H,M,R; Clonality: Polyclonal  |
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Application: |
ELISA WB IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
2.1mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Western blot analysis of Human fetal brain tissue, using GPM6A Polyclonal Antibody at dilution of 1:1050 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
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