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NEDD4L Polyclonal Antibody
RSP5; NEDD4-2; NEDD4.2; hNEDD4-2
货号：YBAP15553 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human NEDD4L | ||
Synonym: |
RSP5; NEDD4-2; NEDD4.2; hNEDD4-2 | ||
| Calculated MW: | |||
| Observed MW: | |||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H,M; Clonality: Polyclonal  |
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Application: |
ELISA IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
2.2mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Immunohistochemistry of Human prostate cancer using NEDD4L Polyclonal Antibody at dilution of 1:50 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
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