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RNF20 Polyclonal Antibody
BRE1; BRE1A; hBRE1
货号：YBAP15656 |
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规格： 50ul/100ul/200ul |
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价格： 980/1280/1890 |
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| Immunogen： | Recombinant protein of human RNF20 | ||
Synonym: |
BRE1; BRE1A; hBRE1 | ||
| Calculated MW: | 114kDa | ||
| Observed MW: | Refer to figures | ||
Source: |
Rabbit | ||
Isotype: |
IgG | Reactivity: H,M; Clonality: Polyclonal  |
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Application: |
ELISA WB IHC | ||
Purify: |
Affinity purification | ||
Concentration: |
1.4mg/ml | ||
Storage Buffer: |
PBS with 0.05% sodium azide, 50% glycerol, pH7.3 | ||
Storage: |
Store at -20℃. Avoid freeze / thaw cycles. |
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| Western blot analysis of Lovo, A172, A375, 231, Jurkat and hela cell, using RNF20 Polyclonal Antibody at dilution of 1:350 |
Protocols： |
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide |
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Background: |
The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor.
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