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CAV1 Polyclonal Antibody
CGL3; PPH3; BSCL3; VIP21; MSTP085
货号:YBAP16591
价格: 980/1280/1890
Immunogen: Synthetic peptide of human CAV1
Synonym:
CGL3; PPH3; BSCL3; VIP21; MSTP085
Calculated MW: 20kD
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M,R;

Clonality: Polyclonal


Application:
ELISA WB
Purify:
Affinity purification
Concentration:
2.1mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
CAV1 Polyclonal Antibody


Western blot analysis of Human leiomyosarcoma tissue, using CAV1 Polyclonal Antibody at dilution of 1:525

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

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