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DIO2 Polyclonal Antibody
D2; 5DII; SelY; DIOII; TXDI2
货号:YBAP16756
价格: 980/1280/1890
Immunogen: Synthetic peptide of human DIO2
Synonym:
D2; 5DII; SelY; DIOII; TXDI2
Calculated MW: 31kDa
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M,R;

Clonality: Polyclonal


Application:
ELISA WB
Purify:
Affinity purification
Concentration:
2.7mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
DIO2 Polyclonal Antibody


Western blot analysis of Mouse brain tissue, using DIO2 Polyclonal Antibody at dilution of 1:200

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.

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