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HIF1AN Polyclonal Antibody
FIH1
货号:YBAP16798
价格: 980/1280/1890
Immunogen: Synthetic peptide of human HIF1AN
Synonym:
FIH1
Calculated MW: 40kDa
Observed MW: Refer to figures
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M;

Clonality: Polyclonal


Application:
ELISA WB IHC
Purify:
Affinity purification
Concentration:
1.6mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
HIF1AN Polyclonal Antibody


Western blot analysis of 231 cell, using HIF1AN Polyclonal Antibody at dilution of 1:250

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene. Hydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins

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