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PSMB8 Polyclonal Antibody
JMP; ALDD; LMP7; NKJO; D6S216; PSMB5i; RING10; D6S216E
货号:YBAP16936
价格: 980/1280/1890
Immunogen: Synthetic peptide of human PSMB8
Synonym:
JMP; ALDD; LMP7; NKJO; D6S216; PSMB5i; RING10; D6S216E
Calculated MW:
Observed MW:
Source:
Rabbit
Isotype:
IgG
Reactivity: H,M;

Clonality: Polyclonal


Application:
ELISA IHC
Purify:
Affinity purification
Concentration:
2.1mg/ml
Storage Buffer:
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
PSMB8 Polyclonal Antibody


Immunohistochemistry of Human esophagus cancer using PSMB8 Polyclonal Antibody at dilution of 1:30

Protocols:
Buffer-Formulation WB-Guide IHC-Guide IP-Guide IF-Guide
Background:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.

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