Alternative Names:

Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor; KLF4; EZF; GKLF;

Application:

WB

Reactivity:

Dilution:

WB 1:1000

	Western blot analysis of extracts from CHO-K1 cells, transfected with pcDNA3.1-Hygro(+)-mKLF4-Flag construct (A) or transfected with pDNA3.1-Hygro(+)-Flag vector (B),using KLF4 mouse mAb (1:1000 diluted).Predicted band size:55/65KDa.Observed band size:55/

Purification:

Affinity-chromatography

Specificity:

KLF4 Mouse mAb detects endogenous levels of total KLF4

Immunogen:

Purified recombinant mouse KLF4 protein fragments expressed in E.coli.

Description:

Plays an important role in maintaining embryonic stem cells,and in preventing their differentiation.Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface.Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.Contributes to the down-regulation of p53/TP53 transcription.

Storage Condition and Buffer:

Mouse IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.