Alternative Names:

CLG1, COLLAGENASE I, NEUTROPHIL, matrix metalloproteinase 8 (neutrophil collagenase)

Application:

WB, , IHC-P, Flow Cyt, IHC-Fr, ICC/IF

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200-P ICC/IF 1:100-1:500

	Western blot analysis of MMP-8 expression in NIH/3T3 cells

Purification:

Affinity-chromatography

Specificity:

MMP-8 Antibody detects endogenous levels of total MMP-8

Immunogen:

A synthesized peptide derived from human MMP-8

Description:

The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.