Alternative Names:

EC 2.7.11.30, TGF-beta receptor type II precursor, TGF-beta type II receptor, TGF-betaR2, TGFR-2, TGFR2, kinase TGF-beta-R2

Application:

WB,IHC

Reactivity:

Human,Mouse

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of TGFBR2 expression in HeLa cells

Purification:

Affinity-chromatography

Specificity:

TGFBR2 Antibody detects endogenous levels of total TGFBR2

Immunogen:

A synthesized peptide derived from human TGFBR2

Description:

Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.