Alternative Names:

Tumor necrosis factor receptor superfamily member 1B [Precursor], Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, CD120b antigen, Etanercept, Tumor necrosis factor receptor superfamily member

Application:

WB,IF

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IF 1:100-1:500

	Western blot analysis of TNF Receptor II expression in HUVEC cell lysate

Purification:

Affinity-chromatography

Specificity:

TNF Receptor II Antibody detects endogenous levels of total TNF Receptor II

Immunogen:

A synthesized peptide derived from human TNF Receptor II

Description:

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.