Alternative Names:

Histone deacetylase 10, HD10

Application:

WB,IHC

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of HDAC10 expression in Cos7 cell extract

Purification:

Affinity-chromatography

Specificity:

HDAC10 Antibody detects endogenous levels of total HDAC10

Immunogen:

A synthesized peptide derived from human HDAC10

Description:

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.