Alternative Names:

Keratin type II cytoskeletal 5, Cytokeratin-5, CK-5, K5, 58 kDa cytokeratin

Application:

WB,IHC

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of Keratin 5 expression in HepG2 cell extract

Purification:

Affinity-chromatography

Specificity:

Keratin 5 Antibody detects endogenous levels of total Keratin 5

Immunogen:

A synthesized peptide derived from human Keratin 5

Description:

Defects in KRT5 are a cause of epidermolysis bullosa simplex Dowling-Meara type (DM-EBS) [MIM:131760]. DM-EBS is a severe form of intraepidermal epidermolysis bullosa characterized by generalized herpetiform blistering, milia formation, dystrophic nails, and mucous membrane involvement.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.