Alternative Names:

CDK4I, CMM2, MLM, MTS1, TP16; p16(INK4), p19, CDK4 inhibitor p16-INK4, alternative reading frame p14, cell cycle negative regulator beta, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A isoform 1,

Application:

WB,IHC,IF

Reactivity:

Human

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500

	Western blot analysis of p14 ARF expression in HeLa cell extract

Purification:

Affinity-chromatography

Specificity:

p14 ARF Antibody detects endogenous levels of total p14 ARF

Immunogen:

A synthesized peptide derived from human p14 ARF

Description:

The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.