Alternative Names:

Alpha platelet-derived growth factor receptor precursor, CD140a, PDGF-R-alpha, PDGFR-alpha, PGFRA, kinase PDGFR-alpha

Application:

WB,IHC,IF

Reactivity:

Human,Mouse,Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500

	Western blot analysis of PDGFR α expression in HepG2 cells

Purification:

Affinity-chromatography

Specificity:

PDGFR α Antibody detects endogenous levels of total PDGFR α

Immunogen:

A synthesized peptide derived from human PDGFR α

Description:

Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.