Alternative Names:

TYR, EC 1.14.18.1, Monophenol monooxygenase, Tumor rejection antigen AB, SK29-AB, LB24-AB

Application:

WB,IHC,IF

Reactivity:

Human

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200 IF 1:100-1:500

	Western blot analysis of Tyrosinase expression in COS7 cells

Purification:

Affinity-chromatography

Specificity:

Tyrosinase Antibody detects endogenous levels of total Tyrosinase

Immunogen:

A synthesized peptide derived from human Tyrosinase

Description:

This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.