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Details
Alternative Names:
AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2Ab;
Application:
WB IHC
Reactivity:
Human Mouse Rat
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200
Western blot analysis of extracts of variouscell lines, using RUNX1antibody. | |
Purification:
Affinity-chromatography
Specificity:
RUNX1 Antibody detects endogenous levels of total RUNX1
Immunogen:
A synthesized peptide derived from human RUNX1
Description:
AML1 (also known as Runx1, CBFA2, and PEBP2αB) is a member of the core binding factor (CBF) family of transcription factors. It is required for normal development of all hematopoietic lineages. AML1 forms a heterodimeric DNA binding complex with its partner protein CBFβ and regulates the expression of cellular genes by binding to promoter and enhancer elements.
Storage Condition and Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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