Alternative Names:

AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2Ab;

Application:

WB IHC

Reactivity:

Human Mouse Rat

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200

	Western blot analysis of extracts of variouscell lines, using RUNX1antibody.

Purification:

Affinity-chromatography

Specificity:

RUNX1 Antibody detects endogenous levels of total RUNX1

Immunogen:

A synthesized peptide derived from human RUNX1

Description:

AML1 (also known as Runx1, CBFA2, and PEBP2αB) is a member of the core binding factor (CBF) family of transcription factors. It is required for normal development of all hematopoietic lineages. AML1 forms a heterodimeric DNA binding complex with its partner protein CBFβ and regulates the expression of cellular genes by binding to promoter and enhancer elements.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.