Alternative Names:

DVL1, DVL, DVL1L1, DSH homolog 1, Dishevelled, Dishevelled-1

Application:

WB IHC

Reactivity:

Human, Mouse,Rat

Dilution:

WB: 1:1000~1:3000 IHC: 1:50~1:200

	Western blot analysis DVL1 using HT-29 whole cell lysates.

Purification:

Affinity-chromatography

Specificity:

DVL1 Antibody detects endogenous levels of total DVL1

Immunogen:

A synthesized peptide derived from human DVL1

Description:

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.