Alternative Names:

connexin 43; Connexin-43; Cx43; CXA1; DFNB38; Gap junction 43 kDa heart protein; Gap junction alpha-1 protein; gap junction protein, alpha 1, 43kDa; gap junction protein, alpha-like; GJA1; GJAL; HSS; ODDD

Application:

WB IHC IF/ICC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200 IF/ICC 1:100~1:500

	Western blot analysis on HuvEc cell lysate using Connexin 43 Antibody

Purification:

Affinity-chromatography

Specificity:

Connexin 43 antibody detects endogenous levels of total Connexin 43

Immunogen:

A synthesized peptide derived from human Connexin 43

Description:

Cx43 an integral membrane protein of the connexin family, alpha-type (group II) subfamily. Hexamers of connexin-43 form connexons, which aggregate together to form gap junctions, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.