Alternative Names:

claudin 2; Claudin-2; CLD2; CLDN2; SP82

Application:

WB IHC IF

Reactivity:

Human, Mouse

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200 IF 1:200

	Western blot analysis on NIH-3T3 cell lysate using Claudin 2 Antibody

Purification:

Affinity-chromatography

Specificity:

Claudin 2 antibody detects endogenous levels of total Claudin 2

Immunogen:

A synthesized peptide derived from human Claudin 2

Description:

claudin 2 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN1, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.