Alternative Names:

ARCC2; ECK; EPH receptor A2; EPHA2; ephrin receptor EphA2; Ephrin type-A receptor 2; Epithelial cell kinase; epithelial cell receptor protein tyrosine kinase; protein tyrosine kinase; soluble EPHA2 variant 1; Tyrosine-protein kinase receptor ECK

Application:

WB IF/ICC

Reactivity:

Human, Rat

Dilution:

WB 1:500-1:2000 IF/ICC 1:100-1:500

	Western blot analysis on HepG2 cell lysate using EPHA2/3/4 Antibody

Purification:

Affinity-chromatography

Specificity:

EPHA2/3/4 Antibody detects endogenous levels of EPHA2/3/4

Immunogen:

A synthesized peptide derived from human EPHA2/3/4

Description:

EphA2 a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 AND -A5. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.