Alternative Names:

DYSF; Dysferlin; dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive); dystrophy-associated fer-1-like 1; Dystrophy-associated fer-1-like protein; Fer-1-like protein 1; FER1L1; FLJ00175; FLJ90168; LGMD2B

Application:

WB

Reactivity:

Human, Mouse

Dilution:

WB 1:500~1:3000

	Western blot analysis on K562 cell lysate using Dysferlin Antibody

Purification:

Affinity-chromatography

Specificity:

Dysferlin antibody detects endogenous levels of total Dysferlin

Immunogen:

A synthesized peptide derived from human Dysferlin

Description:

DYSF Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Belongs to the ferlin family. Interacts with CACNA1S. Interacts with ANXA1; the interaction is Ca(2+)- and injury state-dependent.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.