Alternative Names:

AHF; Antihemophilic factor; Coagulation factor VIII; coagulation factor VIII, procoagulant component; coagulation factor VIIIc; DXS1253E; F8; F8B; F8C; FA8; Factor VIII B chain; factor VIII F8B; Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa hea

Application:

WB IHC

Reactivity:

Human, Mouse

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200

	Western blot analysis on HuvEc cell lysate using Factor VIII Antibody

Purification:

Affinity-chromatography

Specificity:

Factor VIII antibody detects endogenous levels of total Factor VIII

Immunogen:

A synthesized peptide derived from human Factor VIII

Description:

F8 Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. Belongs to the multicopper oxidase family. Interacts with vWF. vWF binding is essential for the stabilization of F8 in circulation.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.