Alternative Names:

EAA3; EEA3; Excitatory amino acid receptor 3; GLR5; GluR-5; GLUR5; Glutamate receptor 5; Glutamate receptor, ionotropic kainate 1; glutamate receptor, ionotropic, kainate 1; GRIK1

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200

	Western blot analysis on mouse brain cell lysate using GluR5 Antibody

Purification:

Affinity-chromatography

Specificity:

GluR5 antibody detects endogenous levels of total GluR5

Immunogen:

A synthesized peptide derived from human GluR5

Description:

GluR5 Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.