Alternative Names:

HEP-NOS; Hepatocyte NOS; Inducible NO synthase; Inducible NOS; iNOS; nitric oxide synthase 2, inducible; nitric oxide synthase 2A (inducible, hepatocytes); Nitric oxide synthase, inducible; nitric oxide synthase, macrophage; NOS; NOS type II; NOS, type II

Application:

WB IHC IF/ICC

Reactivity:

Human

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200 IF/ICC 1:100~1:500

	Western blot analysis on NIH-3T3 cell lysate using iNOS Antibody

Purification:

Affinity-chromatography

Specificity:

iNOS antibody detects endogenous levels of total iNOS

Immunogen:

A synthesized peptide derived from human iNOS

Description:

iNOS Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Belongs to the NOS family. Induced by endotoxins and cytokines. Induced by interferon gamma acting synergistically with lipopolysaccharide, tumor necrosis factor alpha or interleukin-1 beta. Homodimer. Binds SLC9A3R1. 2 isoforms of the human protein are produced by alternative splicing.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.