Alternative Names:

C8orf57; DKFZp761D112; matrix metallopeptidase 16 (membrane-inserted); Matrix metalloproteinase-16; Membrane-type matrix metalloproteinase 3; Membrane-type-3 matrix metalloproteinase; MMP16; MMPX2; MMP16; MMPX2; MT-MMP 3; MT-MMP2; MT-MMP3; MT3-MMP; MT3MMP

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200

	Western blot analysis on HepG2 cell lysate using MMP16 Antibody

Purification:

Affinity-chromatography

Specificity:

MMP16 antibody detects endogenous levels of total MMP16

Immunogen:

A synthesized peptide derived from human MMP16

Description:

MMP16 Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.