Alternative Names:

NF-A1; Oct-1; OCT1; Octamer-binding protein 1; Octamer-binding transcription factor 1; Octamer-binding transcription factor-1; OTF-1; OTF1; PO2F1; POU class 2 homeobox 1; POU domain, class 2, transcription factor 1; POU2F1

Application:

WB IHC

Reactivity:

Human, Mouse

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200

	Western blot analysis on HeLa cell lysate using OCT1 Antibody

Purification:

Affinity-chromatography

Specificity:

OCT1 antibody detects endogenous levels of total 41183

Immunogen:

A synthesized peptide derived from human 41183

Description:

POU2F1 a ubiquitous transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR. Phosphorylation apparently inhibits its interaction with DNA

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.