Alternative Names:

GTP-binding protein Rit1; GTP-binding protein Roc1; MGC125864; MGC125865; Ras-like protein expressed in many tissues; Ras-like without CAAX 1; Ras-like without CAAX protein 1; RIBB; Ric-like, expressed in many tissues; RIT; RIT1; ROC1

Application:

WB

Reactivity:

Human, Mouse

Dilution:

WB 1:500~1:3000

	Western blot analysis on Jurkat cell lysate using RIT1 Antibody

Purification:

Affinity-chromatography

Specificity:

RIT1 antibody detects endogenous levels of total RIT1

Immunogen:

A synthesized peptide derived from human RIT1

Description:

RIT1 Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Belongs to the small GTPase superfamily. Ras family. Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.