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AOS1 Antibody
AOS1 Antibody
Product Introduction
AOS1 Antibody

Details

Alternative Names:

activator of SUMO1; AOS1; FLJ3091; HSPC140; SAE1; sentrin/SUMO-activating protein AOS1; SUA1; SUMO-1 activating enzyme E1 N subunit; SUMO-1 activating enzyme subunit 1; SUMO-activating enzyme subunit 1; SUMO1 activating enzyme subunit 1; Ubiquitin-like 1

Application:

WB IF/ICC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000 IF/ICC 1:100~1:500

Western blot analysis on 293 cell lysate using AOS1 Antibody

Purification:

Affinity-chromatography

Specificity:

AOS1 antibody detects endogenous levels of total AOS1

Immunogen:

A synthesized peptide derived from human AOS1

Description:

UBLE1A The dimeric enzyme acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2. Belongs to the ubiquitin-activating E1 family. Heterodimer of SAE1 and SAE2. The complex binds SUMO proteins via SAE2.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.


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