Alternative Names:

DEN1; deneddylase 1; Deneddylase-1; NEDD8 specific-protease cysteine 2; NEDD8-specific protease 1; NEDP1; Protease, cysteine 2; PRSC2; SENP8; Sentrin-specific protease 8; Sentrin/SUMO-specific protease SENP8; SUMO sentrin specific protease family member

Application:

WB IHC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200

	Western blot analysis on HuvEc cell lysate using SENP8 Antibody

Purification:

Affinity-chromatography

Specificity:

SENP8 antibody detects endogenous levels of total SENP8

Immunogen:

A synthesized peptide derived from human SENP8

Description:

SENP8 Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. Belongs to the peptidase C48 family.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.