Alternative Names:

C-terminal LIM domain protein 1; carboxy terminal LIM domain protein 1; carboxyl terminal LIM domain protein 1; CLIM1; CLP-36; CLP36; Elfin; enigma; hCLIM1; LIM domain protein CLP-36; PDLI1; PDLIM1; PDZ and LIM domain 1; PDZ and LIM domain protein 1

Application:

WB IHC IF/ICC

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200 IF/ICC 1:100~1:500

	Western blot analysis on K562 and Jurkat cell lysate using CLIM1 Antibody

Purification:

Affinity-chromatography

Specificity:

CLIM1 antibody detects endogenous levels of total CLIM1

Immunogen:

A synthesized peptide derived from human CLIM1

Description:

CLIM1 a cytoskeletal adaptor protein that bring other proteins to the cytoskeleton. Interacts with alpha-actinins 1, 2 and 4. Recruits the Clik1 kinase to actin stress fibers in nonmuscle cells. Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.