Alternative Names:

hTIF1; PTC6; RING finger protein 82; RNF82; TF1A; TIF1; TIF1-alpha; TIF1A; TIF1ALPHA; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; TRIM24; tripartite motif protein 24; tripartite motif-containing 24; Tripartite motif-c

Application:

WB IHC

Reactivity:

Human, Mouse

Dilution:

WB 1:500~1:3000 IHC 1:50~1:200

	Western blot analysis on Jurkat and K562 cell lysate using TRIM24 Antibody

Purification:

Affinity-chromatography

Specificity:

TRIM24 antibody detects endogenous levels of total TRIM24

Immunogen:

A synthesized peptide derived from human TRIM24

Description:

TRIM24 an atypical protein kinase that functions as a transcriptional coactivator. Originally identified as a mammalian protein that enhances the AF-2 activity of the retinoid X receptor (RXR) in a yeast genetic screen. Binds to nuclear receptors in an agonist and AF2-activating domain (AF2-AD) dependent manner. Binding to the agonist-nuclear receptor complex induces its own hyperphosphorylation as well as the phosphorylation of TFIIEa, TAFII28, and TAFII55.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.