Alternative Names:

FLJ16340; HBP1; high mobility group box transcription factor 1; HMG box containing protein 1; HMG box transcription factor 1; HMG box-containing protein 1; HMG-box containing protein 1; HMG-box transcription factor 1

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000

	Western blot analysis on A549 cell lysate using HBP1 Antibody

Purification:

Affinity-chromatography

Specificity:

HBP1 antibody detects endogenous levels of total HBP1

Immunogen:

A synthesized peptide derived from human HBP1

Description:

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.