Alternative Names:

DNA polymerase zeta catalytic subunit, DPOLZ, DPOZ, EC 2.7.7.7, POLZ, REV3L, SEZ4, Seizure-related protein 4, hREV3

Application:

IHC

Reactivity:

Human, Mouse,

Dilution:

IHC 1:50-1:200

Purification:

Affinity-chromatography

Specificity:

REV3L Antibody detects endogenous levels of REV3L

Immunogen:

A synthesized peptide derived from human REV3L

Description:

REV3 is the DNA polymerase zeta catalytic subunit. Catalyzes the production of N diphosphate + {DNA}N from N deoxynucleoside triphosphate. Involved in translesion synthesis and required for the production of UV- and other DNA fork-blocking-induced mutations, as well as the majority of spontaneous mutations.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.