Alternative Names:

ADA2; ADA2-like protein; ADA2A; FLJ12705; hADA2; KL04P; TAD2A; TADA2A; TADA2L; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; transcriptional adaptor 2 (ADA2 homolog, yeast)-like; transcriptional adaptor 2 (ADA2, yeast, homolog)-like; t

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000

	Western blot analysis on COLO205 cell lysate using ADA2L Antibody

Purification:

Affinity-chromatography

Specificity:

ADA2L antibody detects endogenous levels of total ADA2L

Immunogen:

A synthesized peptide derived from human ADA2L

Description:

TADA2L Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site. Binds double- stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. Interacts with GCN5 and NR3C1.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.