Alternative Names:

Alpha-synuclein; alpha-synuclein, isoform NACP140; MGC110988; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; SNCA; synuclein, alpha (non

Application:

WB

Reactivity:

Human, Mouse, Rat

Dilution:

WB 1:500~1:3000

	Western blot analysis on mouse brain cell lysate using Alpha-synuclein Antibody

Purification:

Affinity-chromatography

Specificity:

Alpha-synuclein antibody detects endogenous levels of total Alpha-synuclein

Immunogen:

A synthesized peptide derived from human Alpha-synuclein

Description:

SNCA a member of the synuclein family. Abundantly expressed in the brain. Inhibits phospholipase D2 selectively. May integrate presynaptic signaling and membrane trafficking. Implicated in the pathogenesis of Parkinson's disease. A major component of amyloid plaques in the brains of patients with Alzheimer's disease. Two alternatively spliced isoforms transcripts have been identified.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.