Alternative Names:

GG2-1; Head and neck tumor and metastasis-related protein; MDC-3.13; NDED; NF-kappa-B-inducible DED-containing protein; SCC-S2; SCCS2; TFIP8; TNF alpha-induced protein 8; TNF-induced protein GG2-1; TNFAIP8; Tumor necrosis factor alpha-induced protein 8; t

Application:

WB IHC IF/ICC

Reactivity:

Human, Mouse,

Dilution:

WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

	Western blot analysis on HuvEc cell lysate using TFIP8 Antibody

Purification:

Affinity-chromatography

Specificity:

TFIP8 Antibody detects endogenous levels of TFIP8

Immunogen:

A synthesized peptide derived from human TFIP8

Description:

TNFAIP8 Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. Induced by nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.