Alternative Names:

Fast-1; Fast-2; FAST1; FAST2; Forkhead activin signal transducer 1; Forkhead activin signal transducer 2; forkhead activin signal transducer-1; forkhead box H1; Forkhead box protein H1; FOXH1; hFAST-1; TGF-beta/activin signal transducer

Application:

IF/ICC

Reactivity:

Human, Mouse,

Dilution:

IF/ICC 1:100-1:500

Purification:

Affinity-chromatography

Specificity:

FOXH1 Antibody detects endogenous levels of FOXH1

Immunogen:

A synthesized peptide derived from human FOXH1

Description:

FOXH1 Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.