Alternative Names:

Dual specificity protein phosphatase 16; DUS16; DUSP16; EC 3.1.3.16; EC 3.1.3.48; KIAA1700; MAP kinase phosphatase 7; MAP kinase phosphatase-7; Mitogen-activated protein kinase phosphatase 7; MKP7

Application:

WB IF/ICC

Reactivity:

Human, Mouse,

Dilution:

WB 1:500-1:2000 IF/ICC 1:100-1:500

	Western blot analysis on Jurkat cell lysate using DUSP16 Antibody

Purification:

Affinity-chromatography

Specificity:

DUSP16 Antibody detects endogenous levels of DUSP16

Immunogen:

A synthesized peptide derived from human DUSP16

Description:

The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity.[supplied by OMIM]

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.