Alternative Names:

deleted in lung and esophageal cancer 1; Deleted in lung and esophageal cancer protein 1; deleted in lung cancer 1; Deleted in lung cancer protein 1; DLC-1; DLC1; DLEC1; F56

Application:

IHC IF/ICC

Reactivity:

Human,

Dilution:

IHC 1:50-1:200 IF/ICC 1:100-1:500

Purification:

Affinity-chromatography

Specificity:

DLEC1 Antibody detects endogenous levels of DLEC1

Immunogen:

A synthesized peptide derived from human DLEC1

Description:

The DLEC1 (deleted in lung cancer-1) gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced DLEC1 transcripts contain disrupted coding regions and are likely to encode nonfunctional proteins. Aberrant transcription of DLEC1 may be involved in carcinogenesis of the lung, esophagus, and kidney.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.