Alternative Names:

Imprinted in placenta and liver protein Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein Tumor-suppressing STF cDNA 3 protein Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein p17-Beckwith-Wiedemann r

Application:

IHC

Reactivity:

Human,

Dilution:

IHC 1:50-1:200

Purification:

Affinity-chromatography

Specificity:

PHLA2 Antibody detects endogenous levels of PHLA2

Immunogen:

A synthesized peptide derived from human PHLA2

Description:

This gene is one of several genes in the imprinted gene domain of 11p15.5 which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Studies of the mouse gene, however, which is also located in an imprinted gene domain, have shown that the product of this gene regulates placental growth.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.