Alternative Names:

FLJ11136; MGC4288; p300/CBP-associated factor (PCAF)-associated factor 65; PAF65-alpha; PAF65A; PCAF-associated factor 65 alpha; PCAF-associated factor 65-alpha; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; T

Application:

WB

Reactivity:

Human, Mouse,

Dilution:

WB 1:500-1:2000

	Western blot analysis on 293 cell lysate using TAF6L Antibody

Purification:

Affinity-chromatography

Specificity:

TAF6L Antibody detects endogenous levels of TAF6L

Immunogen:

A synthesized peptide derived from human TAF6L

Description:

TAF6L Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Belongs to the TAF6 family. The PCAF complex is composed of a number of TBP- associated factors (TAFS), such as TAF5, TAF5L, TAF6, TAF6L, TAF9, TAF10 and TAF12, PCAF, and also PCAF-associated factors (PAFs), such as TADA2L/ADA2, TADA3L/ADA3 and SPT3. Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.

Storage Condition and Buffer:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.